Magnesium L-Threonate


Magnesium L-Threonate is a compound that combines magnesium, an essential mineral, with L-Threonate, a form of vitamin C. This unique combination is believed to enhance the absorption and bioavailability of magnesium in the body. Magnesium is involved in numerous physiological processes and is crucial for maintaining overall health. It plays a vital role in supporting bone health, muscle function, and energy production. Additionally, magnesium is involved in regulating blood pressure, nerve function, and the synthesis of DNA and protein. L-Threonate, on the other hand, is a naturally occurring sugar derivative that has been shown to enhance the delivery of magnesium across the blood-brain barrier. This barrier protects the brain from potentially harmful substances but can also limit the entry of essential nutrients. By utilizing L-Threonate, magnesium can potentially reach higher concentrations in the brain, where it may exert its beneficial effects. Magnesium L-Threonate is available in supplement form and is gaining popularity as a potential cognitive enhancer. Some studies suggest that this compound may support cognitive function, memory, and overall brain health. It is believed to promote synaptic plasticity, which is essential for learning and memory processes. While more research is needed to fully understand the effects and potential benefits of Magnesium L-Threonate, it is generally considered safe for consumption when used as directed. However, it is always advisable to consult with a healthcare professional before starting any new supplement regimen, especially if you have any pre-existing medical conditions or are taking other medications. In summary, Magnesium L-Threonate is a compound that combines magnesium and L-Threonate, aiming to enhance the absorption and bioavailability of magnesium in the body. It is believed to potentially support cognitive function and brain health, although more research is needed to confirm these claims.

Expert Recommendations:

Dr. Christian Gonzalez recommends incorporating this for brain health and cognitive function, while Dr. Andrew Huberman suggests implementing it to support transition time into sleep and promote deeper sleep.¹²

How Does Iron Compare to Magnesium L-Threonate in Terms of Benefits for the Body?

When comparing the benefits of iron intake to magnesium L-threonate, it’s important to note that both nutrients play distinct roles in the body. While iron is essential for oxygen transport and energy production, magnesium L-threonate supports cognitive function and overall brain health. Both are crucial for optimal bodily function.


• Improved cognitive function: Magnesium L-Threonate has been shown to enhance memory and learning abilities by increasing synaptic density and plasticity in the brain. • Reduced anxiety and stress: This form of magnesium has a calming effect on the nervous system, helping to alleviate anxiety and stress. • Better sleep quality: Magnesium L-Threonate can promote restful sleep by regulating neurotransmitters and reducing insomnia symptoms. • Enhanced mood: By supporting neurotransmitter balance, this supplement can help stabilize mood and alleviate symptoms of depression. • Improved bone health: Magnesium is essential for maintaining strong bones, and Magnesium L-Threonate can contribute to bone density and strength. • Reduced risk of cardiovascular diseases: Adequate magnesium intake has been associated with a lower risk of heart disease, high blood pressure, and stroke. • Alleviation of migraines: This form of magnesium has been found to reduce the frequency and intensity of migraines. • Increased energy levels: Magnesium L-Threonate plays a crucial role in energy production, helping to combat fatigue and increase stamina. • Support for muscle relaxation: Magnesium is known to relax muscles and alleviate muscle cramps, making it beneficial for athletes and individuals with muscle tension. • Improved overall health: Adequate magnesium levels support numerous bodily functions, including metabolism, DNA synthesis, and immune system function.


• Consult with a healthcare professional before starting magnesium L-threonate supplementation, especially if you have any pre-existing medical conditions or are taking any medications. • Pregnant or breastfeeding women should avoid taking magnesium L-threonate unless recommended by a healthcare professional. • Individuals with kidney problems or impaired kidney function should use caution when taking magnesium L-threonate, as it may affect kidney function. • Magnesium L-threonate may interact with certain medications, such as antibiotics, bisphosphonates, diuretics, and muscle relaxants. It is important to check for potential drug interactions before starting supplementation. • Excessive magnesium intake can lead to diarrhea, nausea, stomach cramps, and other digestive issues. Start with a low dosage and gradually increase if necessary to avoid these side effects. • People with a history of low blood pressure should monitor their blood pressure levels closely when taking magnesium L-threonate, as it may further lower blood pressure. • Magnesium L-threonate may have a sedative effect and cause drowsiness. It is recommended to avoid driving or operating heavy machinery until the individual knows how it affects them. • If experiencing any adverse reactions or allergic symptoms after taking magnesium L-threonate, discontinue use and seek medical attention immediately.


1. Magnesium Reviews with Richele Webb 2. Rational Supplementation for Health & Performance

Get the latest health advice from top experts in your inbox, every week.